Invitrogen™ SARS-CoV-2 Omicron Spike Protein S1/S2 (XBB.1) Chimeric Recombinant Human Monoclonal Antibody (D007)

Description

Specifically recognize the SARS-CoV-2 Omicron XBB.1 Spike. No cross-reactivity with SARS-CoV-2 XBB.1.5, XBB, BF.7, BA.4/BA.5/BA.5.2, BA.2.75, BQ.1.1, wild type, Alpha, Beta, Delta.. Has cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1) Spike S1+S2 trimer Protein; No cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1.5) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike RBD Protein; SARS-CoV-2 Omicron (XBB) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB) Spike RBD Protein; SARS-CoV-2 Omicron (BF.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4.6/BF.7) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike RBD Protein; SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein; SARS-CoV-2 Omicron (B.1.1.529) Spike RBD Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; SARS-CoV-2 Delta (B.1.617.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Delta (B.1.617.2) Spike RBD Protein; SARS-CoV-2 Beta (B.1.351) Spike S1+S2 trimer Protein; SARS-CoV-2 Beta (B.1.351, B.1.351.2, B.1.351.3) Spike RBD Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike RBD Protein; SARS-CoV-2 Spike S1+S2 (D614G) trimer Protein; SARS-CoV-2 Spike RBD Protein.

The SARS-CoV-2 Omicron Spike Protein S1/S2 refers to specific regions of the spike (S) protein of the Omicron variant of the SARS-CoV-2 virus, which is responsible for COVID-19. The spike protein is a key component of the virus's structure and plays a critical role in its ability to infect host cells. It is composed of two main subunits: S1 and S2. The S1/S2 designation refers to the cleavage site between these two subunits. This cleavage is a crucial step for the activation of the spike protein, which is necessary for the virus to enter host cells. The cleavage is typically performed by host cell proteases, such as furin. The Omicron variant of SARS-CoV-2 has numerous mutations in the spike protein, including in the S1 and S2 subunits. These mutations can affect the virus's transmissibility, ability to evade the immune response, and the effectiveness of vaccines and treatments.