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p21WAF1 Ab-6 Mouse Monoclonal Antibody, Epredia™

Achieve accurate, reproducible results with the Epredia™ p21WAF1 Ab-6, Mouse Monoclonal Antibody.

Brand:  Epredia MS-454-P1ABX

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Product Code. 12671477

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Description

Description

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: HJ21; same as WA-1

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: PC12, Ls174T or Raji cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Flow Cytometry (Not Suitable)

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY
Specifications

Specifications

p21WAF1 Ab-6
Monoclonal
1mg/mL
Mouse
100 μL
Cancer and Tumor Biology
Human, Rat
IgG1
Immunofluorescence, Western Blot
HJ21; same as WA-1
Unconjugated
Human recombinant p21 protein
RUO
Primary
Concentrated
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