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PKA[C] Mouse, Unlabeled, Clone: 5B, BD

Mouse Monoclonal Antibody

211.00€ - 359.00€

Specifications

Antigen PKA[C]
Clone 5B
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15875739
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BD Biosciences
610980
50 μg
211.00€
1 set
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15885739
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BD Biosciences
610981
150 μg
359.00€
1 set
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Description

Description

cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R). Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ. These subunits define type I and II cAMP-dependent protein kinases. Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active. Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ). Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity. The levels of expression of the different subunits vary according to cell and tissue type.

Immunofluorescence, Western Blotting

Specifications

Specifications

PKA[C]
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2b
Affinity Purified
5B
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Human PKA[Cα] subunit aa. 18-347
Primary
Store undiluted at -20°C.
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For Research Use Only.

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