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  6. CD11b/Mac-1 Mouse anti-Human, APC, Clone: ICRF44, BD

CD11b/Mac-1 Mouse anti-Human, APC, Clone: ICRF44, BD

Mouse Monoclonal Antibody

63.98€ - 376.68€

Specifications

Antigen CD11b
Clone ICRF44
Applications Flow Cytometry
Classification Monoclonal
Conjugate APC
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BD Biosciences
561015 		25 Tests
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BD Biosciences
550019 		100 Tests
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377.00€
376.68€ / Each
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Description

Description

Reacts with the 165kDa adhesion glycoprotein (Mac-1, integrin αM subunit) which associates with the 95kDa integrin β2 (CD18) to form the CD11b/CD18 complex. CD11b/Mac-1 is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and as a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits PMN aggregation in response to fMLP. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: ICRF44
Isotype: IgG1, κ
Cross Reactivity: Human

Flow Cytometry

Specifications

Specifications

CD11b
Flow Cytometry
APC
RUO
Human
Human monocytes
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
ICRF44
Monoclonal
Mouse
Immunology
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
MAC-1A; Mac-1; ITGAM; Integrin alpha M; CR3A; CR-3 alpha; Mo1; SLEB6
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