Immunohistochemistry Kits and Reagents
BD Cytometric Bead Array (CBA) Human Enhanced Sensitivity Master Buffer Kit
Employs particles with discrete fluorescence intensities to detect soluble analytes at very low concentrations
BD Cytometric Bead Array (CBA) Mouse Enhanced Sensitivity Master Buffer Kit
For use in Flow Cytometry
Thermo Scientific™ Metal Enhanced DAB Substrate Kit
Special formulation of diaminobenzidine peroxidase substrate that uses cobalt and nickel chloride to yield intense color for IHC staining.
BD Cytometric Bead Array (CBA) Human IL-17A Standard
Lyophilized recombinant Human Interleukin-17A (IL-17A) protein
BD BV480 Mouse Anti-Human CD45
CD45 is encoded by the PTPRC (Protein tyrosine phosphatase receptor type C) gene. BD Horizon™ BV480 Mouse Anti-Human CD45 is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and thymocytes. CD45 is absent from circulating erythrocytes, platelets, or mature erythroid cells of bone marrow and non-hemopoietic tissues.
BD BV480 Mouse Anti-Human CD45RO
CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells. BD Horizon™ BV480 Mouse Anti-Human CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations. CD45RO binds to CD22.
BD BV480 Mouse Anti-Human CD138
CD138 is strongly expressed on multiple-myeloma-derived cell lines and malignant plasma cell populations. BD Horizon™ BV480 Mouse Anti-Human CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III, and V, tenascin, thrombospondin, and antithrombin III.
BD BV480 Mouse Anti-Human CD1a
CD1a is expressed on cortical thymocytes, dendritic cells and Langerhans cells. BD Horizon™ BV480 Mouse Anti-Human CD1a has structural similarities to the MHC class I antigen, and plays a role in antigen presentation.
BD BV480 Mouse Anti-Human CD5
CD5 is a 67 kDa single-chain, type 1 transmembrane glycoprotein expressed on most thymocytes, the majority of peripheral T lymphocytes and a subpopulation of B cells. BD Horizon™ BV480 Mouse Anti-Human CD5+ B cells produce polyreactive antibodies (mostly IgM).
BD BV480 Rat Anti-Mouse CD44
CD44 is widely expressed on hematopoietic and non-hematopoietic cells. BD Horizon™ BV480 Rat Anti-Mouse CD44 isoforms encoded by variable exons are expressed on epithelial cells, but only at low levels on most leukocytes. Mice with the Ly-24.1 alloantigen (e.g., BALB/c, CBA/J, DBA/1, DBA/2) have relatively large subsets of CD44H+ T lymphocytes.
BD Cytometric Bead Array (CBA) Human Anaphylatoxin Kit
Can be used to quantitatively measure anaphylatoxin C3a, C4a, and C5a (bioactive cleavage products released from C3, C4, and C5 during complement activation) protein levels in a single EDTA plasma or serum sample.
BD BV480 Rat Anti-Mouse CD103
CD103 has a unique and fairly restricted tissue distribution. BD Horizon™ BV480 Rat Anti-Mouse CD103 is expressed on almost all intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells (DEC), subpopulations of peripheral T cells, and distinct subsets of fetal, neonatal, and adult thymocytes.
BD BV480 Mouse Anti-Human CD127
CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells. BD Horizon™ BV480 Mouse Anti-Human CD127 is down-regulated following T cell activation. Studies indicate that the IL-7 Receptor plays an important role in the proliferation and differentiation of mature T cells.
BD BV480 Mouse Anti-Human CD31
CD31 has wide tissue distribution and is expressed on platelets, monocytes, granulocytes, NK cells, T cell subsets, and in high amounts on endothelial cells. BD Horizon™ BV480 Mouse Anti-Human CD31 functions as a vascular endothelial cell adhesion molecule and is involved in the transendothelial migration of leucocytes in inflammatory responses.
BD BV480 Mouse Anti-Human CD3
CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. BD Horizon™ BV480 Mouse Anti-Human CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε