Immunohistochemistry Kits and Reagents
BD Cytometric Bead Array (CBA) Human Enhanced Sensitivity Master Buffer Kit
Employs particles with discrete fluorescence intensities to detect soluble analytes at very low concentrations
BD Cytometric Bead Array (CBA) Mouse Enhanced Sensitivity Master Buffer Kit
For use in Flow Cytometry
BD Cytometric Bead Array (CBA) Human IL-17A Standard
Lyophilized recombinant Human Interleukin-17A (IL-17A) protein
Thermo Scientific™ Metal Enhanced DAB Substrate Kit
Special formulation of diaminobenzidine peroxidase substrate that uses cobalt and nickel chloride to yield intense color for IHC staining.
BD Cytometric Bead Array (CBA) Human Anaphylatoxin Kit
Can be used to quantitatively measure anaphylatoxin C3a, C4a, and C5a (bioactive cleavage products released from C3, C4, and C5 during complement activation) protein levels in a single EDTA plasma or serum sample.
BD BV480 Mouse Anti-Human CD3
CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. BD Horizon™ BV480 Mouse Anti-Human CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε
BD BV480 Rat Anti-Mouse CD117
Widespread expression of CD117 in hematopoietic precursors is consistent with participation of c-Kit and its ligand in regulation of several hematopoietic lineages. BD Horizon™ BV480 Rat Anti-Mouse CD117 is also involved in the regulation of some events during the development of T lymphocytes. CD117 is also expressed by mast cells and by dendritic cells found in the periarteriolar lymphocytoc sheaths (T-cell areas) of splenic white pulp.
BD BV480 Mouse Anti-Human CD27
With its ligand CD70, CD27 acts in a co-stimulatory fashion on T lymphocytes. BD Horizon™ BV480 Mouse Anti-Human CD27 is present on most peripheral blood T lymphocytes and medullary thymocytes and CD27 antigen is upregulated upon activation with the release of a soluble form, 28 to 32 kDa.
BD BV480 Rat Anti-Mouse CD19
Expressed throughout B-lymphocyte development from the pro-B cell through the mature B-cell stages. BD Horizon™ BV480 Rat Anti-Mouse CD19 participates in B-lymphocyte development, B-cell activation, maturation of memory B cells and regulation of tolerance. CD19 has also been detected on peritoneal mast cells, co-localized with CD21/CD35, and it is proposed to play a role in complement-mediated mast-cell activation.
BD BV480 Mouse Anti-Human CD64
CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. BD Horizon™ BV480 Mouse Anti-Human CD64 associates with a signaling FcRγ homodimer to form the functional high affinity FcγRI complex and functions in both innate and adaptive immune responses.
BD BV480 Mouse Anti-Human CD56
CD56 antigen is expressed on approximately 10% to 25% of peripheral blood lymphocytes. BD Horizon™ BV480 Mouse Anti-Human CD56 is present on essentially all resting and activated CD16+ natural killer (NK) lymphocytes and approximately 5% of CD3+ peripheral blood lymphocytes.
BD BV480 Rat Anti-Mouse CD25
CD25 is transiently expressed at a low level during normal B-cell development in the bone marrow on the CD45R/B220low TdT- sIg- Pre-B/Pre-B-II and CD45R/B220low TdT- sIgM+ sIgD- immature B stages. BD Horizon™ BV480 Rat Anti-Mouse CD25 is expressed at a higher level during a very early stage of T-cell development in fetal and adult thymus.
BD BV480 Mouse Anti-Human CD45RA
CD45RA is expressed on approximately 40-50% of peripheral CD4+ T cells, 50% of peripheral CD8+ T cells and on a portion of B cells and monocytes. BD Horizon™ BV480 Mouse Anti-Human CD45RA antigen is expressed by naive and activated T cells. CD45RA-specific antibodies are useful for the study of the suppressor/inducer subpopulation of CD4+ lymphocytes.
BD BV480 Mouse Anti-Human CD38
CD38 is expressed by other cells including monocytes, macrophages, dendritic cells, NK cells, myeloid and erythroid precursors and some epithelial cells. BD Horizon™ BV480 Mouse Anti-Human CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose.
BD BV480 Mouse Anti-Human IgD
mIgD is expressed on mature naive B cells (along with membrane IgM) and serves as a B-cell receptor for antigen (BCR). BD Horizon™ BV480 Mouse Anti-Human IgD BCR, in association with other signaling molecules including CD79a and CD79b, can transduce activating or tolerizing signals intracellularly into B lymphocytes.