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Invitrogen™ VEGF/PlGF Heterodimer Monoclonal Antibody (146213)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561238
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
The VEGF/PlGF heterodimer is a complex formed by the vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), both of which are important members of the VEGF family involved in angiogenesis and vasculogenesis. VEGF is primarily known for its role in promoting the growth of blood vessels, while PlGF is involved in pathological angiogenesis and inflammation. The heterodimerization of VEGF and PlGF can enhance their biological activities, contributing to processes such as wound healing, tumor growth, and the development of certain diseases characterized by abnormal blood vessel formation. This heterodimer has been a target of interest in therapeutic research, particularly in the context of cancer and ocular diseases, where inhibiting its activity could potentially reduce pathological angiogenesis and improve clinical outcomes.
Specifications
| VEGF/PlGF Heterodimer | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| E. coli-derived recombinant human VEGF/PlGF heterodimer, Ala27-Arg191 (VEGF) & Ala21-Arg149 (PIGF). | |
| 500 μg | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 146213 | |
| Unconjugated | |
| Mouse | |
| Protein A/G | |
| RUO | |
| Human | |
| Antibody | |
| IgG2a |
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