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  5. Tocris Bioscience™ Varenicline tartrate

Tocris Bioscience™ Varenicline tartrate

Product Code. 18752504
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10 mg
50 mg
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10mg
50mg
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18752504 50 mg 50mg
18712524 10 mg 10mg
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Product Code. 18752504 Supplier Tocris Bioscience™ Supplier No. 3754/50

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Description

Selective α4β2 partial agonist; orally active

Orally active, subtype-selective partial agonist at α4β2 nicotinic receptors (Ki values are 0.06, 240, 322 and 3540 nM for α4β2, α3β4, α7, α1βγδ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo. Also potently activates PSAM4-5-HT3 and PSAM4-GlyR chimeric ion channels (EC50 values are 4 and 1.6 nM, respectively)
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 375815-87-5
Molecular Formula C17H19N3O6

Specifications

Quantity 50 mg
Formula Weight 361.37
Purity >99%
Molecular Weight (g/mol) 361.354
Chemical Name or Material Varenicline tartrate
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