missing translation for 'onlineSavingsMsg'
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Description
The antibody recognize all 3 isoforms of USP34.
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Specifications
Specifications
| Antigen | USP34 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.13 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | USP34 |
| Gene Accession No. | Q6ZQ93, Q70CQ2 |
| Gene Alias | Deubiquitinating enzyme 34, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34 |
| Gene Symbols | Usp34 |
| Show More |
Product Title
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