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TRIM29 Antibody (TRIM29/1042), Alexa Fluor™ 594, Novus Biologicals™

Product Code. 18155228 Shop All Bio Techne Products
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Product Code. 18155228 Supplier Novus Biologicals Supplier No. NBP247809AF594

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Description

Mouse Monoclonal Antibody

TRIM29 Monoclonal specifically detects TRIM29 in Human samples. It is validated for Western Blot.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM29
Applications Western Blot, Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone TRIM29/1042
Conjugate Alexa Fluor 594
Dilution Western Blot, Flow Cytometry, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias Ataxia telangiectasia group D-associated protein, ATDC, ATDC ataxia-telangiectasia group D-associated protein, FLJ36085, tripartite motif containing 29, tripartite motif protein TRIM29, tripartite motif-containing 29, tripartite motif-containing protein 29
Gene Symbols TRIM29
Host Species Mouse
Immunogen Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein (Uniprot: Q14134)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ∽90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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