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  6. TRIB3 Mouse anti-Human, Mouse, Rat, Clone: 2C10C7, Proteintech

TRIB3 Mouse anti-Human, Mouse, Rat, Clone: 2C10C7, Proteintech

Product Code. 16888825 Shop All Proteintech Products
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150 μL
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20µL
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16888825 20 μL 20µL
16878825 150 μL 150µL
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Product Code. 16888825 Supplier Proteintech Supplier No. 667021IG20UL

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Description

Mouse Monoclonal Antibody

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.

Specifications

Antigen TRIB3
Applications Western Blot
Classification Monoclonal
Clone 2C10C7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TRIB3
Gene Accession No. Q8K4K2, Q96RU7, Q9WTQ6
Gene Alias C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3
Gene Symbols TRIB3
Host Species Mouse
Immunogen TRIB3 Fusion Protein Ag25776
Purification Method Protein G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 228775, 246273, 57761
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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