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Invitrogen™ TPT1 Monoclonal Antibody (488411)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561465
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
Specifications
| TPT1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P13693, P63028, P63029 | |
| TPT1 | |
| E. coli-derived recombinant human TPT1/TCTP, Met1-Cys172. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Western Blot, Immunocytochemistry | |
| 488411 | |
| Unconjugated | |
| TPT1 | |
| 21 kDa polypeptide; 21 kDa polypeptide under translational control; fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 116646, 22070, 7178 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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