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Invitrogen™ TNF alpha Recombinant Rabbit Monoclonal Antibody (101), FITC

Rabbit Recombinant Monoclonal Antibody

99.00€ - 209.00€

Specifications

Antigen TNF alpha
Clone 101
Concentration 0.1 mg/mL
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Applications Flow Cytometry
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
30536127
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Invitrogen™
MA560281
100 Tests
209.00€
Pack of 100
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30535489
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Invitrogen™
MA560282
25 Tests
99.00€
Pack of 25
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Description

Description

TNF alpha Recombinant Monoclonal Antibody for Flow

TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Specifications

Specifications

TNF alpha
0.1 mg/mL
Flow Cytometry
FITC
Rabbit
RUO
PBS with 0.5% BSA and 0.09% sodium azide
P01375
7124
Recombinant Human TNF-alpha protein (Val77-Leu233).
Antibody
101
4°C, store in dark, DO NOT FREEZE!
Recombinant Monoclonal
Liquid
IgG
Human
Tnf
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF α; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFα; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Tnf
Primary
Protein A
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