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TMEM41B Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 29270-1-AP-20UL

Additional Details : Weight : 0.00020kg

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Product Code. 17211446

  • 140.00€ / 20µL
Estimated Shipment: 30-04-2024
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Description

Description

Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.

Specifications

Specifications

TMEM41B
Polyclonal
Unconjugated
20 μL
440026
Liquid
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
400 μg/mL
Rabbit
Primary
Human, Mouse
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