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TCF2 Polyclonal Antibody, Invitrogen™

Product Code. 11521033
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. Quantity unitSize
11521033 50 μg 50µg
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Product Code. 11521033 Supplier Invitrogen Supplier No. PA124459

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Description

Rabbit Polyclonal Antibody

PA1-24459 detects Hepatocyte Nuclear Factor 1-beta (TCF2) in Human samples. PA1-24459 has been successfully used in Western Blot procedures. PA1-24459 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human TCF2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Hepatocyte Nuclear Factor 1? (HNF-1?, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCF2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Gene HNF1B
Gene Accession No. P35680
Gene Symbols HNF1B
Host Species Rabbit
Immunogen Synthetic peptide region of human TCF2.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6928
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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