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SRY Monoclonal Antibody (OTI3C8), TrueMAB™, OriGene
Description
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
Specifications
Specifications
| Antigen | SRY |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | OTI3C8 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | SRY |
| Gene Accession No. | Q05066 |
| Gene Alias | SRXX1, SRXY1, TDF, TDY |
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Product Title
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