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Eurofins DiscoverX Src (1-530) Protein, Active
Description
Src family tyrosine kinases are nonreceptor tyrosine kinases that are functionally linked to some receptor-type tyrosine kinases, G-protein-coupled receptors, cytokine receptors, and cell adhesion molecules/receptors. Src family tyrosine kinases are membrane-associated proteins having Src homology 2 (SH2) and SH3 domains, which are important for protein-protein interaction. The activity of Src family tyrosine kinases is regulated through intramolecular interaction between the SH2 domain and the phosphorylated tyrosine at the C-terminal regulatory site (Tyr-527).
EMBL K03218
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 61.1 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥75% |
| Protein | Src (1-530), active |
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