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SOX2 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Product Code. p-7088502 Shop All Proteintech Products
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150 μL
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16807893 20 μL 20µL
16897883 150 μL 150µL
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Product Code. 16807893 Supplier Proteintech Supplier No. 110641AP20UL

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Rabbit Polyclonal Antibody

This antibody is a rabbit polyclonal antibody raised against an internal region of human SOX2. a rare undifferentiated cell population that is intermingled with the Bergmann glia of the adult murine cerebellar cortex, expresses the stem cell markers Sox2

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintece in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Specifications

Antigen SOX2
Applications Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SOX2
Gene Accession No. P48431, P48432, Q6P0E1
Gene Alias ANOP3, MCOPS3, SOX2, Transcription factor SOX 2
Gene Symbols sox2
Host Species Rabbit
Immunogen SOX2 Fusion Protein Ag1530
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20674, 378723, 499593, 6657
Target Species Human, Zebrafish, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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