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SCN4B Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16816905 Shop All Proteintech Products
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150 μL
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16816905 20 μL 20µL
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Product Code. 16816905 Supplier Proteintech Supplier No. 554381AP20UL

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Rabbit Polyclonal Antibody

The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation By similarity. The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy.

Specifications

Antigen SCN4B
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SCN4B
Gene Accession No. Q7M729, Q8IWT1
Gene Alias SCN4B, Sodium channel subunit beta 4
Gene Symbols Scn4b
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 399548, 6330
Target Species Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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