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ACROBiosystems SARS-CoV-2 (COVID-19) S1 protein (N501Y), His Tag
Brand: ACROBiosystems S1N-C52Hg-100ug
This item is not returnable.
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Description
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.9 kDa. The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| QHD43416.1 (N501Y) | |
| 100 μg | |
| Val 16 - Arg 685 | |
| Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,COVID-19 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE. |
| 76.9 kDa | |
| SARS-CoV-2 S1 protein (N501Y), His Tag (S1N-C52Hg) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (N501Y)). N501Y mutaion was identified in both the SARS-CoV-2 variant (known as 20 B/501 Y.V1, VOC 202012/01, or B0.1.1.7 lineage) which emerged in the United Kindom and SARS-CoV-2 variant (known as 20 C/501 Y.V2 or B0.1.351 lineage) which emerged in South Africa. | |
| -20°C | |
| S1 protein | |
| SARS-CoV-2 | |
| PBS, pH7.4 | |
| HEK293 | |
| Viral Proteins |