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R&D Systems™ Recombinant Human Thrombopoietin/TPO Protein, Animal-Free

Product Code. 30306042
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Quantity:
1 mg
50 μg
Unit Size:
1mg
50µg
This item is not returnable. View return policy

Product Code. 30306042

Brand: R&D Systems™ BTTPOAFL01M

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This item is not returnable. View return policy

Recombinant Protein

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al. (1988) Br. J. Haematol. 69:359. The ED50 for this effect is 0.050-0.500 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 107 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number NP_000451.1
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with Trehalose.
Gene ID (Entrez) 7066
Molecular Weight (g/mol) M.W.-theoretical: 19 kDa, M.W.-observed: 18-19 kDa, under reducing conditions.
Quantity 1 mg
Source E. coli-derived human Thrombopoietin/Tpo protein Ser22-Leu195 Produced using non-animal reagents in an animal-free laboratory.
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1 μg of the protein by the LAL method.
Gene Alias Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, megakaryocyte stimulating factor, MGDF, MGDFC-mpl ligand, MKCSF, MK-CSF, ML, MPL ligand, MPLLG, MPLLGMGC163194, Myeloproliferative leukemia virus oncogene ligand, THCYT1, THPO, thrombopoietin, thrombopoietin nirs variant 1, Tpo, TPOMKCSF
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in water.
Purity or Quality Grade Antigen Affinity-purified
Protein Thrombopoietin/THPO
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