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R&D Systems™ Recombinant Human GDNF Protein

Product Code. 18798229
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Formulation:
Lyophilized from a 0.2μm filtered solution in PBS
Lyophilized from a 0.2μm filtered solution in PBS with BSA as carrier protein
Unit Size:
1mg
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Product Code. 18798229

Brand: R&D Systems™ 212GD01M/CF

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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity, Binding Activity

Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ) at 1 μg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.

Order Info

Ships at ambient temperature.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number P39905
Formulation Lyophilized from a 0.2μm filtered solution in PBS
Gene ID (Entrez) 2668
Molecular Weight (g/mol) 11.6 kDa (monomer)
Quantity 1 mg
Source Mouse myeloma cell line,NS0-derived human GDNF protein Arg109-Ile211
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Regulatory Status RUO
Endotoxin Concentration <1.0 EU per 1μg of the protein by the LAL method
Biological Activity 2 to 12ng/mL
Product Type Recombinant protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Purity or Quality Grade >97%, by SDS-PAGE under reducing conditions and visualized by silver stain
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For Research Use Only

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