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RB1 (phospho S795) Rabbit anti-Human, Polyclonal , Abnova™
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq]
Specifications
Specifications
| Antigen | RB1 (phospho S795) |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic phosphopeptide of human RB1. |
| Dilution | Immunofluorescence (1:100-1:200) Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene Alias | OSRC/RB/p105-Rb/pRb/pp110 |
| Gene Symbols | RB1 |
| Host Species | Rabbit |
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