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RB1 (phospho S795) Rabbit anti-Human, Polyclonal , Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human RB1.

Brand:  Abnova PAB29612.100uL

Product Code. 16214330

  • 406.00€ / 100µL

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Description

Description

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq]

Specifications

Specifications

RB1 (phospho S795)
Polyclonal
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human RB1.
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
RB1
A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S795 of human RB1.
100 μL
Primary
RB1 (phospho S795) polyclonal antibody detects endogenous level of RB1 only when phosphorylated at serine 795.
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunofluorescence (1:100-1:200) Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
OSRC/RB/p105-Rb/pRb/pp110
Rabbit
Affinity Chromatography
RUO
5925
Human
Liquid
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