Invitrogen™ RAE1 alpha/beta/gamma Monoclonal Antibody (199215)

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

RAE1 (RNA Export 1) is a gene that encodes a protein involved in the nuclear export of mRNA in eukaryotic cells. The RAE1 protein is a key component of the mRNA export machinery, facilitating the transport of mRNA from the nucleus to the cytoplasm, where it can be translated into proteins. Variants of this gene, including RAE1 alpha, beta, and gamma, represent different isoforms or homologs that may have distinct roles or regulatory mechanisms in various tissues or developmental stages. Proper functioning of RAE1 is essential for maintaining normal cellular activities and gene expression. Disruptions or mutations in the RAE1 gene can lead to defects in mRNA export, potentially resulting in various diseases, including neurodevelopmental disorders and cancer. Research into RAE1 and its isoforms continues to be important for understanding the complexities of mRNA transport and its implications in health and disease.