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Invitrogen™ RAE1 alpha/beta/delta/epsilon Monoclonal Antibody (199205)
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Product Code. 30533643
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Quantity:
500 μg
Unit Size:
500µg
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30533643 500 μg 500µg
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Product Code. 30533643 Supplier Invitrogen™ Supplier No. MA561040

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Description

Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

RAE1 (RNA Export 1) is a gene that plays a pivotal role in the nuclear export of mRNA in eukaryotic cells. This gene encodes a protein that is integral to the mRNA export machinery, ensuring the proper transport of mRNA from the nucleus to the cytoplasm for translation. The gene has several isoforms, including RAE1 alpha, beta, delta, and epsilon, which may have unique or overlapping functions in different tissues or developmental stages. The proper functioning of RAE1 and its isoforms is crucial for maintaining normal cellular processes and gene expression. Disruptions or mutations in the RAE1 gene can lead to significant defects in mRNA export, potentially causing a range of diseases, including neurodevelopmental disorders and cancers. Ongoing research into RAE1 and its various isoforms is essential for a deeper understanding of mRNA transport mechanisms and their broader implications in cellular health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAE1 alpha/beta/delta/epsilon
Applications Flow Cytometry, Inhibition Assays
Classification Monoclonal
Clone 199205
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Host Species Rat
Immunogen BaF3 mouse pro-B cell line transfected with Rae-1 beta (Accession # NP_033043) and Mouse myeloma cell line NS0-derived recombinant mouse Rae-1 delta Leu29-Ser227 (Accession # Q9JI58).
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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