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WASF1 (phospho Y125), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16090728
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Quantity:
100 μL
Unit Size:
100µL
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16090728 100 μL 100µL
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Product Code. 16090728 Supplier Abnova Supplier No. PAB7913.100uL

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of WASF1.

The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

Antigen WASF1
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of WASF1.
Dilution ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
Gene WASF1
Gene Alias FLJ31482/KIAA0269/SCAR1/WAVE/WAVE1
Gene Symbols WASF1
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y125 of human WASF1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8936
Test Specificity This sequence has high homology with similar regions in rat and mouse WAVE1, and has less than 50% homology to similar regions in the conserved site in WAVE2 (Tyr-124) and WAVE3 (Tyr-125).
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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