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RPS6KB1 (phospho S434), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of RPS6KB1.
Brand: Abnova PAB12645.100ug
Description
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq
Sequence: IRSPRSpecifications
| RPS6KB1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic phosphopeptide of RPS6KB1. | |
| In TBS, pH 7.2 (BSA, 10% Proclin300) | |
| PS6K/S6K/S6K1/STK14A/p70(S6K)-alpha/p70-S6K/p70-alpha | |
| Rabbit | |
| 100 μg | |
| Primary | |
| This antibody recognizes ∼70 KDa of human RPS6KB1. It does not recognize non-phosphorylated peptides. | |
| Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user. | |
| RPS6KB1 | |
| RPS6KB1 | |
| Synthetic phosphopeptide corresponding to residues surrounding S434 of human RPS6KB1. | |
| RUO | |
| 6198 | |
| Human, Mouse, Rat | |
| Liquid |
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