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ACO1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of ACO1.
Brand: Abnova PAB18049.100ug
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Description
Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq]
Specifications
| ACO1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of ACO1. | |
| In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) | |
| P21399 | |
| ACO1 | |
| A synthetic peptide corresponding to human ACO1. | |
| RUO | |
| 48 | |
| Human, Mouse, Rat | |
| Liquid |
| ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (PFA fixed) | |
| Unconjugated | |
| Immunohistochemistry (1:50∼1:100) Immunofluorescence (1:500∼1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user. | |
| ACO1 | |
| ACONS/IREB1/IREBP/IREBP1/IRP1 | |
| Rabbit | |
| 100 μg | |
| Primary | |
| This antibody is specific to ACO1. | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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