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Tocris Bioscience™ PS 1145 dihydrochloride

Produktkod. 18760779
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10 mg
50 mg
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10mg
50mg
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Produktkod. 18760779 Leverantör Tocris Bioscience™ Leverantörsnummer 4569/10

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Beskrivning

Selective IKK inhibitor; orally active

PS 1145 dihydrochloride is a selective IκB kinase (IKK) inhibitor (IC50 = 100 nM). Has no effect on PKA, PKC and CKII activity. Inhibits IκB-α phosphorylation and NFκB activation in HeLa cells. Inhibits NFκB-mediated proinflammatory gene expression in human airway epithelial cells. Enhances TNF-α-induced apoptosis in a multiple myeloma cell line. Attenuates LPS-induced TNF-α production in vivo. Orally active.
TRUSTED_SUSTAINABILITY

Specifikationer

Purity >98%
Quantity 10 mg
Product Type PS 1145 dihydrochloride
Molecular Weight (g/mol) 395.67
Inhibitors PS 1145 dihydrochloride

For Research Use Only

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