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  6. p21/CIP1/CDKN1A Antibody (CIP1/823 + DCS-60.2) - Azide and BSA Free, Novus Biologicals™

p21/CIP1/CDKN1A Antibody (CIP1/823 + DCS-60.2) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

591.00€

Specifications

Antigen p21/CIP1/CDKN1A
Clone CIP1/823 + DCS-60.2
Concentration 1.0 mg/mL
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
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Novus Biologicals
NBP2-47897-0.1MG 		0.1 mg
591.00€
0.10mg
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Description

Description

p21/CIP1/CDKN1A Monoclonal specifically detects p21/CIP1/CDKN1A in Human, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications

Specifications

p21/CIP1/CDKN1A
1.0 mg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Unconjugated
Mouse
Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair
PBS with No Preservative
1026
Recombinant full-length human CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2)
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
21 kDa
CIP1/823 + DCS-60.2
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Monoclonal
Purified
RUO
Human, Mouse (Negative), Rat (Negative)
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
CDKN1A
IgG
Protein A or G purified
This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
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