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P-selectin Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16861444 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16861444 20 μL 20µL
16851444 150 μL 150µL
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Product Code. 16861444 Supplier Proteintech Supplier No. 133041AP20UL

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Description

Rabbit Polyclonal Antibody

P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.

Specifications

Antigen P-selectin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SELP
Gene Accession No. P16109
Gene Alias CD62, CD62P, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, P-selectin, SELP
Gene Symbols SELP
Host Species Rabbit
Immunogen P-selectin Fusion Protein Ag4124
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6403
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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