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NPM1, Mouse anti-Human, Clone: NPM1/3286, Novus Biologicals™

Mouse Monoclonal Antibody

281.00€ - 523.00€

Specifications

Antigen NPM1
Clone NPM1/3286
Concentration 0.2 mg/mL
Dilution Western Blot 1-2 ug/ml, Flow Cytometry 1-2 ug/million cells, ELISA 2-4 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
18293778
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Novus Biologicals
NBP2-79740-20UG
20 μg
281.00€
20µg
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18223588
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Novus Biologicals
NBP2-79740-100UG
100 μg
523.00€
100µg
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Description

Description

NPM1 Monoclonal specifically detects NPM1 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.
Specifications

Specifications

NPM1
0.2 mg/mL
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
10 mM PBS with 0.05% BSA
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
NPM1
IgG1 κ
Protein A or G purified
This antibody recognizes a 33kDa glycoprotein, identified as Nucleophosmin (NPM1). It is predominantly localized in the nucleus of cells in most tissues. NPM1 is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
NPM1/3286
Western Blot 1-2 ug/ml, Flow Cytometry 1-2 ug/million cells, ELISA 2-4 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Monoclonal
Purified
RUO
Human
P06748, P06748
4869
Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Primary
Store at 4°C.
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