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NFAT5 Polyclonal Antibody, Invitrogen™
Description
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
Specifications
Specifications
| Antigen | NFAT5 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | NFAT5 |
| Gene Accession No. | O94916, Q9WV30 |
| Gene Alias | Nuclear Factor Activated T-Cells, NFATL1, Nuclear factor of activated T cells 5, T cell transcription factor NFAT5, NF-AT5, Tonicity-responsive enhanc |
| Gene Symbols | NFAT5 |
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Product Title
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