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Invitrogen™ NEDD8 Monoclonal Antibody (866916)

Rat Monoclonal Antibody
Brand: Invitrogen™ MA561500
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Specifications
| NEDD8 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and no preservative | |
| P29595, Q15843, Q71UE8 | |
| Nedd8 | |
| E. coli-derived recombinant human NEDD8, Leu2-Gly77. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2b |
| Western Blot, Immunocytochemistry | |
| 866916 | |
| Unconjugated | |
| Nedd8 | |
| nedd8; NEDD-8; NEDD8 ubiquitin like modifier; nedd8.L; nedd8.S; neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; neural precursor cell expressed, developmentally down-regulated 8; neural precursor cell expressed, developmentally down-regulated 8 L homeolog; neural precursor cell expressed, developmentally down-regulated 8 S homeolog; neural precursor cell expressed, developmentally down-regulated gene 8; neural precursor cell-expressed developmentally down-regulated; Rub1; si:zc14a17.5; ubiquitin; ubiquitin-like protein Nedd8; XELAEV_18007009mg | |
| Rat | |
| Protein A/G | |
| RUO | |
| 18002, 25490, 4738 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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