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PLN, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a partial recombinant PLN.
Brand: Abnova H00005350-A01.50uL
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Description
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]
Sequence: MEKVQYLTRSAIRRASTIEMPQQARQKLQNSpecifications
| PLN | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a partial recombinant PLN. | |
| PLN | |
| CMD1P/PLB | |
| Mouse | |
| 50 μL | |
| Primary | |
| Human | |
| Antisera |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| BC005269 | |
| PLN | |
| PLN (AAH05269, 1 a.a. ∽ 30 a.a) partial recombinant protein with GST tag. | |
| RUO | |
| 5350 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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