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Description
The 13-11 monoclonal antibody specifically recognizes Troponin T type 2 (cardiac), encoded by the gene TNNT2 . Troponin T is the tropomyosin-binding subunit of the troponin complex, which also encompasses troponin C and troponin I. This complex regulates muscle contraction in skeletal and cardiac muscle in response to alterations in calcium levels. Troponin T type 2 is solely found in the heart, and genetic alterations in the TNNT2 gene are associated to a series of heart disorders in humans, including hypertrophic cardiomyopathy, dilated cardiomyopathy and left ventricular noncompaction. Cardiac Troponin T can be used as a marker for the identification of cardiomyocytes derived from pluripotent stem cells.
Specifications
| Cardiac Troponin T | |
| Monoclonal | |
| 0.2mg/mL | |
| cTnT, Cardiac Muscle Troponin T, Troponin T type 2, TNNT2 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Canine, Chicken, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat | |
| IgG1 κ |
| Flow Cytometry, Immunofluorescence, Immunocytochemistry | |
| 13-11 | |
| Alexa Fluor 647 | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| Rabbit cardiac troponin T Protein | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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