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Invitrogen™ MIOS Monoclonal Antibody (955413)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA562013
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt].
Specifications
| MIOS | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q8VE19, Q9NXC5 | |
| MIOS | |
| Human MIOS synthetic peptide. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Western Blot | |
| 955413 | |
| Unconjugated | |
| MIOS | |
| C81488; FLJ20323; GATOR complex protein MIOS; H_DJ1159O04.1; meiosis regulator for oocyte development; MIO; Mios; Missing oocyte meiosis regulator homolog; missing oocyte, meiosis regulator, homolog; missing oocyte, meiosis regulator, homolog (Drosophila); RGD1308432; Sea4; WD repeat-containing protein mio; WUGSC:H_DJ1159O04.1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 252875, 362324, 54468 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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