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MINA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12214-1-AP-20UL
This item is not returnable.
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Description
MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.Specifications
| MINA | |
| Polyclonal | |
| Unconjugated | |
| RIOX2 | |
| MDIG, MINA, Mina53, MYC induced nuclear antigen, NO52, Nucleolar protein 52 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 266670, 67014, 84864 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation | |
| 0.23 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8CD15, Q8CFC1, Q8IUF8 | |
| RIOX2 | |
| MINA Fusion Protein Ag2838 | |
| 20 μL | |
| Primary | |
| Rat, Mouse, Human | |
| Antibody | |
| IgG |
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