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Invitrogen™ HTRA2 Monoclonal Antibody (229926)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA560985

Product Code. 30534009

  • 459.00€ / 100µg

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Description

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HTRA2
Monoclonal
0.5 mg/mL
PBS with trehalose and no preservative
O43464
HTRA2
E. coli-derived recombinant human HTRA2/Omi, Ala134-Glu458.
100 μg
Primary
Human
Antibody
IgG2b
Western Blot, Immunocytochemistry
229926
Unconjugated
HTRA2
AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI
Mouse
Protein A/G
RUO
27429
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Lyophilized
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