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  6. MFN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

MFN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16832194 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16832194 20 μL 20µL
16822194 150 μL 150µL
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Product Code. 16832194 Supplier Proteintech Supplier No. 137981AP20UL

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Description

Rabbit Polyclonal Antibody

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

Specifications

Antigen MFN1
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MFN1
Gene Accession No. Q811U4, Q8IWA4, Q8R4Z9
Gene Alias Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1
Gene Symbols MFN1
Host Species Rabbit
Immunogen MFN1 Fusion Protein Ag4762
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192647, 55669, 67414
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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