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Invitrogen™ MD-1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5148486
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.
Specifications
| MD-1 | |
| Polyclonal | |
| Unconjugated | |
| LY86 | |
| dJ80N2.1; Ly86; Ly-86; Lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 17084 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| O88188 | |
| LY86 | |
| Mouse myeloma cell line NS0-derived recombinant mouse MD-1, Asp20-Ser162. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
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