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MCAM/CD146 Antibody (SPM620), Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-44510-0.1MG
This item is not returnable.
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Description
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
MCAM/CD146 Monoclonal specifically detects MCAM/CD146 in Human, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications
| MCAM/CD146 | |
| Monoclonal | |
| 0.2mg/mL | |
| Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml | |
| CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin | |
| Mouse | |
| 130 kDa | |
| 0.1 mg | |
| Cancer, Mesenchymal Stem Cell Markers, Stem Cell Markers | |
| 4162 | |
| Human | |
| Purified |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence | |
| SPM620 | |
| Unconjugated | |
| 10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| MCAM | |
| Recombinant human MCAM protein | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. | |
| Store at 4C. | |
| IgG1 κ |
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