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Invitrogen™ MASTL Polyclonal Antibody

Product Code. 30535768
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
30535768 100 μg 100µg
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Product Code. 30535768 Supplier Invitrogen™ Supplier No. PA5148462

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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MASTL
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene MASTL
Gene Accession No. Q96GX5
Gene Alias 2700091H24Rik; C88295; GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; Mastl; MAST-L; microtubule associated serine/threonine kinase like; microtubule associated serine/threonine kinase-like; microtubule-associated serine/threonine-protein kinase-like; RP11-85G18.2; Serine/threonine-protein kinase greatwall; THC2
Gene Symbols MASTL
Host Species Goat
Immunogen E. coli-derived recombinant human MASTL., Lys39-Lys158.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84930
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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