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Invitrogen™ MASTL Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5148462
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
Specifications
| MASTL | |
| Polyclonal | |
| Unconjugated | |
| MASTL | |
| 2700091H24Rik; C88295; GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; Mastl; MAST-L; microtubule associated serine/threonine kinase like; microtubule associated serine/threonine kinase-like; microtubule-associated serine/threonine-protein kinase-like; RP11-85G18.2; Serine/threonine-protein kinase greatwall; THC2 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 84930 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| Q96GX5 | |
| MASTL | |
| E. coli-derived recombinant human MASTL., Lys39-Lys158. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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