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Eurofins DiscoverX LKB1/STRADα/MO25α Protein, Active

Product Code. 17320404
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10 μg
125 μg
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125µg
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17320404 10 μg 10µg
17330404 125 μg 125µg
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Product Code. 17320404 Supplier Eurofins DiscoverX Supplier No. 14596

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Description

Active, recombinant full-length human LKB1 with an N-terminal 6His tag. Provided as a complex with GST-STRADα and GST-MO25α, for use in Kinase Assays.

LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers.

GenBank NM000455 / GenBank AF308302 / GenBank NM_016289

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 52.1 kDa (LKB1), 76.1 kDa (STRADα) and 66.8 kDa (MO25α)
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His / N-terminal GST / N-terminal GST
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade Combined ≥80%
Protein LKB1/STRADα/MO25α, active
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