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Invitrogen™ LECT1 Monoclonal Antibody (394002)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561398
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
ChM-1 is a cartilage-specific matrix glycoprotein that stimulates the growth of chondrocytes. ChM-1 inhibits angiogenesis by disrupting the tube formation of endothelial cells and thus is responsible for the avascular nature of cartilage. ChM-1 is strongly expressed by the proliferating and hypertrophic zones in the epiphyseal plate of long bones. ChM-1 accumulates in the interterritorial matrix around the lacunae. During development, downregulation of ChM-1 permits angiogenesis and ultimately bone formation on the cartilage template. ChM-1 expression is downregulated in the presence of several growth factors including TGFβ2, FGF2 and PTHLH. ChM-1 expression may also play a role in the hypovascularity and chondroid formation of pleomorphic adenomas. The gene encoding human ChM-1 maps to chromosome 13q14-q21.
Specifications
| LECT1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| O75829 | |
| CNMD | |
| Mouse myeloma cell line NS0-derived recombinant human Chondromodulin-1 mature chain, Glu215-Val333. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Western Blot | |
| 394002 | |
| Unconjugated | |
| CNMD | |
| BRICD3; BRICHOS domain containing 3; CHM1; Chm-1; Chmi; CHM-I; Chondromodulin; Chondromodulin 1; chondromodulin I; chondromodulin-1; Chondromodulin-I; Chondrosurfactant protein; CH-SP; Cnmd; LECT1; leukocyte cell derived chemotaxin 1; leukocyte cell-derived chemotaxin 1; multiple myeloma tumor suppressor 1; MYETS1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 11061 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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