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Description
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | LARG |
| Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.49 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | ARHGEF12 |
| Gene Accession No. | Q9NZN5 |
| Gene Alias | ARHGEF12, KIAA0382, LARG, Leukemia associated RhoGEF, PRO2792 |
| Gene Symbols | ARHGEF12 |
| Show More |
Product Title
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