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Description
PAX-5 is a B cell specific activator protein (BSAP). In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20. PAX-5 is expressed primarily inpro-, pre-, and mature B cells, but not in plasma cells. Interestingly, PAX-5 mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis. Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis. This indicates that PAX-5 is important in B cell development, but may also have a role in proper neuronal development.
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat. Others not tested.
Epitope: C-terminal
Immunogen: Synthetic peptide derived from C-terminus of human PAX-5 protein
Molecular Weight: 50kDa
Positive Control: Tonsil, Raji cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Specifications
Specifications
| Antigen | PAX-5 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Clone | Polyclonal |
| Concentration | 200µg/mL |
| Conjugate | Unconjugated |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide derived from C-terminus of human Pax-5 protein |
| Quantity | 1 mL |
| Regulatory Status | IVD |
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Product Title
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