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  7. 12623667

Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.

Brand:  Epredia RM-9101-S0

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Product Code. 12623667

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Description

Description

Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Clone: SP1

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor

Molecular Weight: 67 kDa

Positive Control: Breast CA, MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence (Not verified)
  • Flow Cytometery (Not verified)
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Estrogen Receptor (SP1)
Monoclonal
Unconjugated
Synthetic peptide derived from C-terminal of human estrogen receptor
IVD
Primary
Concentrated
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
SP1
Rabbit
100 μL
Steroids Hormones and Growth Factors
Hamster, Human, Mouse
IgG
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