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KIR2DL3/CD158b2 Antibody (GL183), Novus Biologicals™

Product Code. 18075705 Shop All Bio Techne Products
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Quantity:
0.025 mg
0.1 mg
Unit Size:
0.1mg
25µg
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18075705 0.1 mg 0.1mg
18234961 0.025 mg 25µg
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Product Code. 18075705 Supplier Novus Biologicals Supplier No. NB100658750.1MG

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Description

Mouse Monoclonal Antibody

KIR2DL3/CD158b2 Monoclonal specifically detects KIR2DL3/CD158b2 in Human samples. It is validated for Flow Cytometry, Immunoprecipitation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIR2DL3/CD158b2
Applications Flow Cytometry, Immunoprecipitation
Classification Monoclonal
Clone GL183
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500
Formulation PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide
Gene Accession No. P43628
Gene Alias CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor
Gene Symbols KIR2DL3
Host Species Mouse
Immunogen NK cell clone E57
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Apoptosis
Primary or Secondary Primary
Gene ID (Entrez) 3804
Test Specificity NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1
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