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KCNJ11 (phospho T224) Rabbit anti-Human, Mouse, Polyclonal , Abnova™

Product Code. 16224350
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Quantity:
100 μL
Unit Size:
100µL
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16224350 100 μL 100µL
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Product Code. 16224350 Supplier Abnova Supplier No. PAB29633.100uL

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human KCNJ11.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). [provided by RefSeq]

Specifications

Antigen KCNJ11 (phospho T224)
Applications Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human KCNJ11.
Dilution Immunofluorescence (1:100-1:500) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias BIR/HHF2/IKATP/KIR6.2/MGC133230/PHHI/TNDM3
Gene Symbols KCNJ11
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T224 of human KCNJ11.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3767
Test Specificity KCNJ11 (phospho T224) polyclonal antibody detects endogenous levels of human KCNJ11 only when phosphorylated at threonine 224.
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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